Amidino and guanidino phosphonates

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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Details

424272, 424273R, 548341, 548119, C07D27720

Patent

active

041906640

ABSTRACT:
Amidine phosphonates carrying an unsaturated nitrogen heterocycle-containing substituent, representative of which are N-methyl-N'-[2-(2-thiazolylmethylthio)ethyl]amidinophosphonic acid monoethyl ester and N'-methyl-N"-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]guanidinophosphon ic acid monobenzyl ester, are histamine H.sub.2 -antagonists.

REFERENCES:
patent: 3950333 (1976-04-01), Durant et al.
patent: 4025527 (1977-05-01), Durant et al.
Derwent Abstract 65003y (Belgian Pat. No. 852,324).

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