Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1979-08-27
1981-08-04
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
548111, 548119, 546 22, 546 24, 544243, C07F 958, C07F 965, A61K 31675
Patent
active
042822130
ABSTRACT:
Amidine phosphonates carrying an unsaturated nitrogen heterocycle-containing substituent, representative of which are N-methyl-N'-[2-(2-thiazolylmethylthio)ethyl]amidinophosphonic acid monoethyl ester and N'-methyl-N"-[2-((5-methyl-4-imidazolyl)-methylthio)ethyl]guanidinophospho nic acid monobenzyl ester, are histamine H.sub.2 -antagonists.
REFERENCES:
patent: 3950333 (1976-04-01), Durant et al.
patent: 4025527 (1977-05-01), Durant et al.
patent: 4118502 (1978-10-01), Durant et al.
patent: 4163781 (1979-08-01), Cragoe et al.
Durant Graham J.
Tashma Zev
Young Rodney C.
Foggio Richard D.
Harkaway Natalia
Keps Joan S.
Lourie Alan D.
Rotman Alan L.
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