Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-07-07
1994-07-19
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514339, 548505, 546273, A61K 3140, A61K 3144, C07D20908, C07D21306
Patent
active
053310055
ABSTRACT:
Amidines derived from 3-aminoethyl indoles of formula (I) ##STR1## where R.sub.1 is an atom of hydrogen or a lower alkyl or alkenyl group: R.sub.2 is an atom of hydrogen or a lower alkyl or alkenyl , aryl, arylalkyl or cycloalkyl group; R.sub.3 and R.sub.4 may be the same or different and are an atom of hydrogen or a lower straight or branched chain alkyl group; and R.sub.5 is an atom of hydrogen; a straight or branched chain alkyl, alkenyl or alkynyl group, which may be substituted with an hydroxy group, alkoxy, alkoxycarbonyl, carboxyl, trifluoromethyl, halogen, carbonyl, cyano; a cyano group, phenyl, aryl, cycloalkyl, heterocycle or arylalkyl, optionally substituted with a hydroxy, alkoxy, halogen, amino, alkoxycarbonyl, carboxyl, trifluoromethyl, carbonyl, cyano, nitro, lower alkyl, lower alkenyl, or may form an optionally substituted heterocycle with R.sub.4 and with the nitrogen atom; and the physiologically acceptable salts thereof.
REFERENCES:
patent: 4816470 (1989-03-01), Dowle et al.
patent: 4994483 (1991-02-01), Oxford et al.
Barjoan Pere Dalmases
Bosch Rovira Anna
Caldero Ges Jose M.
Marquillas Olondriz Francisco
Roca Acin Joan Maria
McKane Joseph K.
Ramsuer Robert W.
Vita-Invest S.A.
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