Amidines

Details Amidines Amidines

1983-05-09

1984-12-11

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602457, 42424854, 424267, 424274, 544 585, 544142, 546199, 548422, A61K 3140, C07D40304

Patent

active

044877692

ABSTRACT:
Mitomycin A, mitomycin C, and porfiromycin react with amide acetals and other amide derivatives to produce amidine derivatives having antitumor activity against experimental animal tumors. The amidines derived from mitomycin C are useful intermediates in reactions with primary amines to produce both known and novel 7-amino-9a-methoxymitosanes having antitumor activity against experimental animal tumors.

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