Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-15
1997-10-07
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514422, 514392, 514321, 514274, 514424, 514327, 514509, 514506, 549464, 549 21, 549 19, 549449, 549414, 549378, 548550, 548526, 5483117, 5483241, 5483644, 548256, 5482632, 548225, 548233, 548182, 548199, 5483051, 548251, 548243, 548245, 548213, 548214, 548132, 548133, 548127, 548129, 548135, 548138, 546197, 546221, 546187, 546188, 546210, 546208, 546153, 546163, 544316, 544296, 544298, 544330, 544322, 544238, 544405, 544408, 544364, 544370, 544372, 544182, 544219, 544215, 544180, 544 586, 544 587, 544 585,
Patent
active
056748949
ABSTRACT:
The current invention discloses novel amidine derivatives with nitric oxide donating property that can inhibit platelet aggregation and promote vasodilation in a single compound.
REFERENCES:
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4661111 (1987-04-01), Ruoslahti et al.
patent: 4683291 (1987-07-01), Zimmerman et al.
patent: 4857508 (1989-08-01), Adams et al.
patent: 5220050 (1993-06-01), Bovy et al.
patent: 5239113 (1993-08-01), Bovy et al.
patent: 5254573 (1993-10-01), Bovy et al.
patent: 5272162 (1993-12-01), Tjoeng et al.
patent: 5314902 (1994-05-01), Tjoeng et al.
patent: 5344837 (1994-09-01), Tjoeng et al.
patent: 5344957 (1994-09-01), Bovy et al.
patent: 5354738 (1994-10-01), Tjoeng et al.
patent: 5378727 (1995-01-01), Bovy et al.
Grant & Hackh's Chemical Dictionary, 5th Ed., McGraw-Hill, (1987) p. 394.
Moncada, S. et al. Biochem. Pharm. 38, 1709-1715 (1989).
Wessberg et al. Europ. J. Pharmacol. 106, 59-67 (1985).
Alspaugh, J.A. et al. Infection and Immunity 59, 2291-2296 (1991).
Wallace, J.L. et al. Europ. Jour. Pharm., 257, 249-255 (1994).
MacIntyre, I. et al. Proc. Natl. Acad. Sci. USA, 88 2936-2940 (1991).
Kozcewiak, M. et al. Biochem. 23, 1767-1774 (1984).
Plow, E.F. et al., Proc. Natl. Acad. Sci. 82, 8057-8061 (1985).
Ruggeri, Z.R. et al. Proc. Natl. Acad. Sci. 83, 5708-5712 (1986).
Ginsberg, M. et al. J. Biol. Chem. 260 (7) 3931-3936 (1985).
Haverstick, D.M. et al. Blood 66 (4), 946-952 (1985).
Ruoslati, E. et al. Science 238, 491-497 (1987).
Currie Mark G.
Tjoeng Foe S.
Zupec Mark E.
Bennett D. A.
G.D. Searle & Co.
Shah Mukund J.
Wong King Lit
LandOfFree
Amidine derivatives useful as platelet aggregation inhibitors an does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amidine derivatives useful as platelet aggregation inhibitors an, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amidine derivatives useful as platelet aggregation inhibitors an will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2357717