Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1976-12-27
1978-07-11
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
A61K 31455
Patent
active
041002890
ABSTRACT:
A novel cysteine thiolactone of nicotinamide is disclosed having the formula: ##STR1## The compounds, homo-cysteine thiolactone of nicotinamide, and its pharmacologically acceptable salts have the useful pharmacological activity of lowering cholesterol, free fatty acid and triglyceride plasma level in the case of altered lipid metabolism and improving BSP clearance ratio in cases of liver injury.
A synthesis of the compound from nicotinoyl chloride, hydrochloride or nicotinic acid esters is described as well as modes for the administration of the compound.
REFERENCES:
patent: 3155672 (1964-11-01), Pasini et al.
patent: 3758485 (1973-09-01), Biniecki et al.
Adams Bruce L.
Burns Robert E.
Friedman Stanley J.
Lobato Emmanuel J.
Sigma-Tau
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