Amides useful for treating pain

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S256000, C514S317000, C514S318000, C514S332000, C546S192000, C546S193000, C546S255000, C540S567000

Reexamination Certificate

active

07129235

ABSTRACT:
The present invention relates to compounds of formula (I-VII)or a pharmaceutically acceptable salt or prodrug thereof, in which A, L, R6, R7and R8are defined herein. The present invention also relates to methods of trating pain using these compounds and pharmaceutical compositions including these compounds.

REFERENCES:
patent: 1 437 344 (2004-07-01), None
patent: 2003/192673 (2003-07-01), None
patent: 02/08221 (2002-01-01), None
patent: 03/066595 (2003-08-01), None
patent: 03/074520 (2003-09-01), None
patent: 04/011441 (2004-02-01), None
Patent Abstracts of Japan, vol. 2003, No. 11, Nov. 2003.
Database Chemcats Apr. 23, 2003, retrieved from STN Database accession No. 2003: 3693665; 2003:3693659, 2003: 3693658 and other compounds from AsInEx Express Platinum Collection abstract.
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Hayes, et al., “Cloning and functional expression of a human orthologue of rat vanilloid receptor-1,” Pain 88:205-215 (2000).
Nolano, et al., “Topical capsaicin in humans: parallel loss of epidermal nerve fibers and pain sensation,”Pain81:135-145 (1999).
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