Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to antibody or antibody fragment or immunoglobulin;...
Patent
1978-11-29
1981-07-21
Hunt, Brooks H.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Attached to antibody or antibody fragment or immunoglobulin;...
424 1, 424 9, 2605005H, 564183, 564184, A61K 4900, A61K 4300, C07C10337
Patent
active
042798876
ABSTRACT:
Certain radioiodine containing amides useful as brain imaging agents are disclosed. The compounds of the subject invention are represented by the formula ##STR1## wherein I is a radioisotope of iodine with I-123 being preferred, R.sub.1 and R.sub.2 are the same or different and are selected from the grooup consisting of hydrogen, hydroxy, alkyl, aryl, substituted aryl, aralkyl, anilino and carbamoylmethyl or R.sub.1 and R.sub.2 taken together with the nitrogen to which they are attached form a 5- or 6-membered ring.
REFERENCES:
patent: 4021224 (1977-03-01), Pallos et al.
patent: 4123554 (1978-10-01), Kawada et al.
patent: 4139605 (1979-02-01), Felder et al.
Tubis et al., Int. J. Appl. Rad. Isot., 15:397-400 (1964).
Elias et al., Int. J. Appl. Rad. Isot., 24:463-469 (1973).
Blau et al., Int. J. Appl. Rad. Isot., 3:217-225 (1958).
Hanson et al., J. Med. Chem., 21:830-833 (1978).
Holman et al., J. Lab. Comp. Radio Pharm., 16:69-71 (1979).
Baldwin Ronald M.
Lin Tz-Hong
Winchell Harry S.
Epstein William H.
Gould George M.
Hunt Brooks H.
Medi--Physics, Inc.
Nucker Christine M.
LandOfFree
Amides useful as brain imaging agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amides useful as brain imaging agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amides useful as brain imaging agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2433060