Amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-

Details Amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid- Amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-

1977-12-27

1979-05-15

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424270, C07D27728

Patent

active

041547349

ABSTRACT:
This invention relates to novel amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-7,7-dioxide having the Formula I: ##STR1## wherein R.sub.1 is hydrogen, halogen or lower alkyl; R.sub.2 is hydrogen, lower alkyl or aryl; Ar is aryl or heterocyclic; to the pharmaceutically acceptable salts thereof; and to processes for their preparation. The compounds of this invention exhibit antiinflammatory activity.

REFERENCES:
patent: 3957812 (1976-05-01), Rossignol et al.
patent: 4011236 (1977-03-01), Grier

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