Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-03-23
1996-12-10
Northington Davis, Zinna
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514252, 514269, 514299, 514309, 514312, 514337, 514341, 514343, 514352, 514348, 544298, 544405, 546112, 546141, 546153, 5462684, 546261, 5462714, 5462721, 5462784, 5462787, 5462814, 5462837, 5462844, 546296, 546309, 5462801, 5462697, 5462707, 5462711, 5462744, 5462761, 5462791, 5462754, 5462811, 5462841, 5462831, 5462747, 5462774, 5462777, C07D41402, C07D21302, A61K 3144
Patent
active
055831478
ABSTRACT:
This invention provides amide compounds as inhibitors of acyl-Coenzyme A: cholesterol O-acyltransferase (ACAT), pharmaceutical compositions containing such compounds, processes for the preparation of such compounds, and the use of such compounds as antihypercholesterolemic and/or antiatherosclerotic agents.
REFERENCES:
patent: 2461119 (1949-02-01), Lott et al.
patent: 3039930 (1962-06-01), Gray
patent: 3165527 (1965-01-01), Gray
Heitmeier, J. Med. Chem., vol. 7, No. 3, pp. 288-293, 1964.
Aeilmann et al, Chemical Abstracts, vol. 115, Abstract No. 232,153y, 1991, p. 94.
O'Dell et al, J. of Pharm. Exp. Therp., Jan. Apr. 1960, vol. 128, pp. 65-74.
Gray et al, J. of Amer. Chem. Soc., Jul. 5, 1959, vol. 81, No. 13, pp. 4347-4350.
Khalaj et al, Synthesis, vol. 12, 1985, pp. 1153-1155.
Boswell George A.
DeLucca Indawati
Kezar, III Hollis S.
Ko Soo S.
Li Hui-Yin
Davis Zinna Northington
The DuPont Merck Pharmaceutical Company
LandOfFree
Amides for the treatment of atherosclerosis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amides for the treatment of atherosclerosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amides for the treatment of atherosclerosis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-424499