Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-04-30
1998-05-12
Achutamurthy, Ponnathapura
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 9, 514 8, 530318, 530345, 530322, 530321, 930190, A61K 3814, C07K 750
Patent
active
057505098
ABSTRACT:
The present invention is directed to novel antibiotic A 40926 derivatives characterized by having a carboxy, (C.sub.1 -C.sub.4) alkoxy-carbonyl, aminocarbonyl, (C.sub.1 -C.sub.4) alkylaminocarbonyl, di (C.sub.4 -C.sub.4)alkylaminocarbonyl or hydroxymethyl substituent on the N-acylaminoglucuronyl moiety and a hydroxy or a polyamine substituent in position 63 of the molecule. The compounds of the invention show high in vitro activity against glycopeptide resistant Enterococci and Staphylococci.
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Ciabatti Romeo
Malabarba Adriano
Marazzi Alessandra Maria
Panzone Gianbattista
Achutamurthy Ponnathapura
Dixon J. Michael
Gruppo Lepetit S.p.A.
Wessendof T. D.
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