Amide derivatives, compositions and use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Para-n-benzene - sulfoxy-n containing doai – and said benzene...

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Details

514156, 5142375, 514330, 514616, 544159, 546226, 564 49, 564154, A61K 3116, A61K 31535, C07D245192, C07C31728

Patent

active

051108089

ABSTRACT:
The invention concerns novel (oxamido- and ureido-phenylsulfonyl)nitromethane derivatives and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives.

REFERENCES:
patent: 3326663 (1967-06-01), Soloway et al.
patent: 4412024 (1983-10-01), Avar et al.

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