Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1996-09-06
1998-05-19
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514847, 514463, 5142312, 564160, 564159, 564152, 424401, 560250, 554 57, 554 61, 554 66, 549452, 544175, A61K 3116, A61K 31335, A61K 600, C07C23300
Patent
active
057537070
ABSTRACT:
An amide derivative represented by the following formula (1): ##STR1## wherein R.sup.1 represents a C.sub.1-40 hydrocarbon; R.sup.2 represents a C.sub.1-6 alkylene; R.sup.3 represents H, OH or alkoxyl; R.sup.4 represents a C.sub.1-39 hydrocarbon; R.sup.5 represents ##STR2## with the proviso that when R.sup.5 represents ##STR3## R.sup.3 does not represent OH; and a composition of the amide derivative for topical application to human skin. The composition improves the barrier function of the stratum corneum, providing improvement and prevention of dermatitis, skin roughness, or similar disorders.
REFERENCES:
patent: 4985547 (1991-01-01), Yano et al.
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patent: 5206020 (1993-04-01), Critchley et al.
patent: 5208355 (1993-05-01), Scott
patent: 5446027 (1995-08-01), Fujimori et al.
Arai Youichi
Hase Tadashi
Hoshino Masahide
Kusuoku Hiroshi
Meguro Shinichi
Kao Corporation
Lambkin Deborah
Raymond Richard L.
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