Amide derivatives and methods for using the same as selective ne

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514665, 514670, A01N 3308

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active

060489006

ABSTRACT:
Amide derivatives and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.

REFERENCES:
patent: 2109698 (1938-03-01), Harman
patent: 2186769 (1940-01-01), Schrim
patent: 4123530 (1978-10-01), Corvi-Mora
patent: 5506258 (1996-04-01), Christophe et al.
patent: 5552411 (1996-09-01), Downing et al.
patent: 5554621 (1996-09-01), Poindexter et al.
patent: 5571921 (1996-11-01), Bender et al.
patent: 5602024 (1997-02-01), Gerald et al.
patent: 5635503 (1997-06-01), Poindexter et al.
Prager, B. et al. Verlag Von Julius Springer, 4th ed. vol. IX, p. 213, "Beilsteins Handbuch der Organischen Chemie" (1926) (Translation Enclosed).
Boit, Springer-Verlag, p. 251 "Beilsteins Handbuch der Oranische Chemie, Viertes Erganzungswerk, Vierter Band, Erster Teil" 2-Methoxy-N-methyl-acetamid, N-Methyl-2-methylmercapto-acetamid (1977) (Translation enclosed).
Hellstrom et al., Chem. Ber., vol. 69, pp. 1999-2003 "Ueber Alkyl-thioglykolsaure-anilide bzw.-p-toluidide and entsprechende Thionyl-Verbindungen" (1936) (Translation enclosed).
Lambling, Bull.Chem.Soc.Fr., vol. 17, pp. 356-362 "Action de l'isocyanate de phenyle sur quelques acides-ethers" (1897) (Translation enclosed).
Budavari, S. et al. The Merck Index, p. 10, "Merck Research Laboratories, 47. Acetanilide" (1996).
Ghosh et al. Curr. Sci., vol. 42, No. 3, pp. 92-94 Synthesis and pharmacology of simple analogues of reserpine (tertiary aminoacetyl derivatives of aniline and m-methoxyaniline) (1973).
Vasvari-Debreczy et al., Tetrahedron, vol. 37, No. 24, pp. 4337-4342, "Oxidative cyclization of 2-pyrrolidinylacetamide and 2-pyrrolidinyl-propionamide local anaesthetics" (1981).
Larocca et al., Journal of Pharmaceutical Sciences, vol. 54, No. 4, pp. 654-655 "Synthesis of Some SubstitutedAminoactylbenzamides for Pharmacological Study" (1965).
El-Barbary et al., Tetrahedron, vol. 38, No. 3, pp. 405-412 "Enamine chemistry-XXIV. Synthesis, Thiation and Reduction of Lactams" (1982).
Oklobdzija et al., Journal of Heterocyclic Chemistry, vol. 20, No. 7, pp. 1335-1338.backslash. "Synthesis of pyrazolo[4.3-d]oxazoles from 1-(2,4-dinitrophenyl)-3-methyl-5-pyrazolon-4- oxime" (1983).
Maas et al., Rec.Trav.Chim. Pays-Bas, vol. 74, No. 2, pp. 175-180 "The action of diazoacetic ester on pyridone-2" (1955).
Reiter, Tetrahedron Let., vol. 26, No. 29, pp. 3423-3426 "A general synthesis of 4(5)-acylimidazoles from 4-acylaminoisoxazoles" (1985).
Cornforth et al., Tetrahedron Let., vol. 23, No. 21, pp. 2213-2216 "Failure to verify a reported synthesis of the aconitine skeleton" (1982).
Baker et al. J. Med. Chem., vol. 10, No. 6, pp. 1129-1133 "Irreversible enzyme inhibitors. CVII. Proteolytic Enzymes. I. Bulk tolerance within chymotrypsin-inhibitor complexes" (1967).
Duffin et al., J. Chem. Soc., pp. 734-739 Anhyro-compounds from nitrogen-containing derivatives of thioglycollic acid. Part I. Pyridine and Quinoline compounds (1951).
Misra, J. Org. Chem, vol. 23, pp. 897-899 "Certain thiazolo-benzimidazoles and thiazino-benzimidazoles" (1958).
Metz et al., Tetrahedron, vol. 50, No. 13, pp. 3951-3966 "Claisen rearrangement of N-Silyl Ketene N,O-Acetals Generated from Allyl N-Phenylimidates" (1994).
El-Sherief et al., J. Indian Chem. Soc., vol. 60, No. 1 pp. 58-60 "Synthesis of Some New Benzoxazole, Benzthiazole and Benzimidazole Derivatives with Biological Activity" (1983).
Mahmoud et al., J. Indian Chem. Soc., vol. 59, No. 5 "Synthesis and Biological Activity of Some New 2-(N-Substituted Carboxamidomethyl Thio)-Naphth[1-2,-d]Oxazoles-Part V" (1982).
U.S. Patent Application Serial No. 09/023,351 filed on Feb. 13, 1998 discloses a family of NPY5 Receptor Antagonists. The Patent Application and the above-referenced U.S. Patent Application are commonly owned.
Nair, Indian Journal of Chemistry, vol. 21B, pp. 4-7, Synthesis of .sub.1,1 -Diamino-2-acylethylenes-Sulphine Contraction Route (1982).

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