Amide derivatives

Details Amide derivatives Amide derivatives

1988-06-29

1990-05-22

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

564157, 564165, 514211, 514212, 514213, 5142242, 5142268, 5142275, 5142305, 5142378, 514307, 514311, 514317, 514331, 514365, 514367, 514374, 514375, 514415, 514416, 514522, 514616, 540450, 540467, 540544, 540607, 544 585, 544162, 546196, 546226, 548540, 558414, A61K 3116, A61K 31165, C07C10320

Patent

active

049278363

ABSTRACT:
The invention concerns novel phenoxyacetic acid amide derivatives of the formula I (and pharmaceutically acceptable salts thereof) in which R.sup.1 is hydrogen or fluoro, R.sup.2 is phenyl, cycloalkyl, alkyl or alkenyl as defined herein, and R.sup.3 is hydrogen, methyl or ethyl, or R.sup.2 and R.sup.3 together form polymethylene as defined herein. The invention also includes pharmaceutical compositions containing the amide derivatives, means for the manufacture of the said derivatives and for their use in the treatment of obesity and related conditions and/or in the manufacture of novel medicaments.

REFERENCES:
patent: 4263323 (1981-04-01), Carlsson et al.
patent: 4460580 (1984-07-01), Ostermayer et al.
patent: 4478849 (1984-10-01), Ainsworth et al.
Duckworth et al., "Substituted (phenoxypropylaminoethoxyphenoxy)acetamides", CA, 104, 224722r, Jun. 23, 1986.

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