Amide derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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Details

260465D, 260562B, 424324, A61K 31165, A61K 31275, C07C103127, C07C12178

Patent

active

041917758

ABSTRACT:
The disclosure relates to novel 3,4-disubstituted-branched-chain-fluorinated-acylanilides, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess antiandrogenic activity. Representative of the compounds disclosed is 4-nitro-3-trifluoromethyl-(2-hydroxy-2-trifluoromethylpropionyl)anilide.

REFERENCES:
patent: 3794683 (1974-02-01), Gassner et al.
patent: 3875229 (1975-04-01), Gold

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