Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-05-05
2008-11-18
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S234000
Reexamination Certificate
active
07452908
ABSTRACT:
This invention relates to compounds which are represented by the general formula [I][in which A stands for a group of the following formula [ao] or [b0]Ar1, Ar2and Ar3stand for optionally substituted phenyl; k stands for 0 or 1; m, n and s stand for 0, 1 or 2; R1stands for hydrogen or optionally substituted lower alkyl; R2, R3, R4and R5either stand for hydrogen or optionally substituted lower alkyl, or R2and R3, or R4and R5together stand for trimethylene and the like; R60stands for hydrogen, alkyl, or the like; R61and R71either stand for alkyl and the like, or together stand for trimethylene and the like; X stands for carbonyl or methylene; Y stands for nitrogen or methine; and Q−stands for anion], and the like.The compounds of the invention exhibit selective antagonism to muscarinic M3receptors, and therefore are useful as safe and effective agents showing little side effect, for treating diseases of the respiratory, urinary and digestive systems.
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Fujikawa Toru
Kimura Toshifumi
Naya Akira
Noguchi Kazuhito
Numazawa Tomoshige
Banyu Pharmaceutical Co. Ltd.
Chang Celia
Wenderoth , Lind & Ponack, L.L.P.
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