Amide compounds and methods of using the same

Details Amide compounds and methods of using the same Amide compounds and methods of using the same

2007-07-24

2007-07-24

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C514S210030, C514S212010, C514S237500, C514S255030, C514S330000, C514S604000, C514S605000, C514S620000, C540S484000, C544S162000, C544S386000, C546S226000, C548S566000, C548S953000, C564S092000, C564S099000, C564S165000

Reexamination Certificate

active

10508791

ABSTRACT:
Disclosed is a compound having the formula (I) pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists

REFERENCES:
patent: 4139623 (1979-02-01), Jaeggi et al.
patent: 2003/0153541 (2003-08-01), Dudley et al.
patent: 2003/0162758 (2003-08-01), Schwartz et al.
patent: 2003/0229062 (2003-12-01), Schwartz et al.
patent: 2004/0072868 (2004-04-01), Collins et al.
patent: 2004/0266663 (2004-12-01), Schwartz et al.
patent: 2005/0036992 (2005-02-01), Saez et al.
patent: 2005/0107444 (2005-05-01), Thompson et al.
patent: 2005/0113580 (2005-05-01), Thompson et al.
patent: 2005/0131014 (2005-06-01), Collini et al.
patent: 2005/0171084 (2005-08-01), Cairns et al.
patent: 2005/0282750 (2005-12-01), Schwartz et al.
patent: 2005/0282908 (2005-12-01), Collins et al.
patent: 0 394 440 (1990-10-01), None
patent: WO 00/54759 (2000-09-01), None
patent: WO 01/60818 (2001-08-01), None
patent: WO 02/24632 (2002-03-01), None
patent: WO 03/082192 (2003-10-01), None
patent: WO 03/082205 (2003-10-01), None
patent: WO 03/082802 (2003-10-01), None
patent: WO 04/ 058819 (2004-07-01), None
patent: WO 04/110368 (2004-12-01), None
patent: WO 04/110375 (2004-12-01), None
patent: WO 05/009383 (2005-02-01), None
patent: WO 05/013946 (2005-02-01), None
patent: WO 05/055998 (2005-06-01), None
patent: WO 06/000576 (2006-01-01), None
patent: WO 06/000577 (2006-01-01), None
patent: WO 06/004030 (2006-01-01), None
U.S. Appl. No. 60/499,659, Hoang et al., filed Sep. 3, 2003.
U.S. Appl. No. 60/500,295, Hoang et al., filed Sep. 4, 2003.
U.S. Appl. No. 60/499,779, Kallander et al., filed Sep. 3, 2003.
U.S. Appl. No. 60/500,296, Kallander et al., filed Sep. 4, 2003.
U.S. Appl. No. 60/499,762, Hoang et al., filed Sep. 3, 2003.
Grefhorst et al.Am. J. Physiol. Endocrinol. Metab.,289: E829-E838 (2005).
Groot et al.J. Lipid Res.,46: 2182-2191 (2005).
Jaye et al.J. Med. Chem.,48: 5419-5422 (2005).
Ogawa et al.J. Med. Chem.,96: e59-e67 (2005).
Quninet et al.J. Lipid Res.,45: 1929-1942 (2004).
Miao et al.J. Lipid Res.,45: 140-1417 (2004).
Schmuth et al.J. Invest. Dermatol.123: 41-48 (2004).
Farnegardh et al.J. Biol. Chem.,278(40): 38821-38828 (2003).
Wang et al.J. Molec. Graphics and Modelling,22: 173-181 (2003).
Fowler et al.J. Invest. Dermatol.,120: 246-255 (2003).
Joseph et al.PNAS USA,99(11): 7604-7609 (2002).
Fluhr et al.J. Invest Dermatol.,125: 1206-1214 (2005).
Naik et al.Circulation,113: 90-97 (2006).
Kruit et al.Gastroenterology,128: 147-156 (2005).
Laffitte et al.PNAS USA,100(9): 5419-5424 (2003).
Castrillo et al.J. Biol. Chem.,278(12): 10443-10449 (2003).
Laffitte et al.Mol. & Cell. Biol.,23(6): 2182-2191 (2003).
Collins et al.J. Med. Chem.,45: 1963-1966 (2002).
Terasaka et al.FEBS Journal,272: 1546-1556 (2005).
Collins et al.Abstracts of Papers, 230thACS National Meeting, Washington, DC. Aug. 28-Sep. 1, 2005. MEDI-237. Publisher: American Chemical Society, Washington, DC.
Rao et alAbstracts of Papers, 229thACS National Meeting, San Diego, CA. Mar. 13-17, 2005. COMP-258. Publisher: American Chemical Society, Washington, DC.
Jon L. CollinsAbstracts of Papers, 225thACS National Meeting, New Orleans, LA. Mar. 23-27, 2003. MEDI-152. Publisher: American Chemical Society, Washington, DC.
Collins et al.Abstracts of Papers, 223rdACS National Meeting, Orlando, FL. Apr. 7-11, 2002. MEDI-123. Publisher: American Chemical Society, Washington, DC.
Angelo Gavezzotti. Acc. Chem. Res., 27: 309-314 (1994).
Vippagunta et al. Advanced Drug Delivery Reviews, 48: 3-26 (2001).
Office Action: U.S. Appl. No. 10/508,849, filed Feb. 5, 2007.

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