Amide and urea derivatives having anti-hypercholesteremic activi

Details Amide and urea derivatives having anti-hypercholesteremic activi Amide and urea derivatives having anti-hypercholesteremic activi

1996-02-27

1997-03-25

Higel, Floyd D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514357, 514399, 514400, 514500, 514585, 514586, 514587, 514588, 514589, 514596, 514597, 514598, 549354, 549388, 549390, 5483381, 564 48, 564 49, 564 52, 564176, 564179, A61K 31335, A61K 3117, A61K 3124, C07D31300, C07C23500, C07C23700

Patent

active

056145500

ABSTRACT:
Compounds of formula (I) are provided: ##STR1## wherein: R.sup.1 represents an alkyl group; or a group of formula (II), (III), (IV) or (V): ##STR2## and wherein the groups R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are hydrogen or various organic groups; and pharmaceutically acceptable salts thereof; as well as methods for the preparation of such compounds and their use in the treatment and prophylaxis of hypercholesteremia and arteriosclerosis.

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patent: 5015644 (1991-05-01), Roth et al.
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Kumazawa et al, Chemical Abstracts, vol. 117, #233877z (1992).
Lythgoe, Chemical Abstracts, vol. 117, #69592w (1992).
Sekiya et al, Chemical Abstracts, vol. 116, #6541n (1992).
Yoshida et al, Chemical Abstracts, vol. 119, #180658c (1993).

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