Amidated insulin glargine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S006200, C514S006500, C514S007200, C514S011700, C530S303000, C530S308000

Reexamination Certificate

active

08048854

ABSTRACT:
The invention relates to insulin glargine which is modified by amidation, especially Gly(A21), Arg(B31), Arg amide (B32) human insulin (insulin glargine amide).

REFERENCES:
patent: 5227293 (1993-07-01), Stengelin et al.
patent: 5656722 (1997-08-01), Dorschug et al.
patent: 5663291 (1997-09-01), Obermeier et al.
patent: 6528486 (2003-03-01), Larsen et al.
patent: 6875589 (2005-04-01), Dorschug et al.
patent: 2006/0120969 (2006-06-01), Nilsson et al.
patent: 0132769 (1985-02-01), None
patent: 0214826 (1987-03-01), None
patent: 0254516 (1988-01-01), None
patent: 0294851 (1988-12-01), None
patent: 0140084 (1990-06-01), None
patent: 0229998 (1992-07-01), None
patent: 0376156 (1996-03-01), None
patent: WO 01/04156 (2001-01-01), None
patent: WO 02/066628 (2002-08-01), None
patent: WO 02/068660 (2002-09-01), None
patent: WO 02/070722 (2002-09-01), None
patent: WO 03/044210 (2003-05-01), None
patent: WO 03/105888 (2003-12-01), None
patent: WO 2004/005342 (2004-01-01), None
patent: WO 2006/015879 (2006-02-01), None
patent: WO 2006/058620 (2006-06-01), None
patent: WO 2007/036299 (2007-04-01), None
Barnett, A., et. al. , Insulin Analogues, The Lancet, vol. 349, pp. 47-51, (1997).
Hartmann, H., et. al., Biological Activity of des-B26-1330)-Insulinamide and Related Analogues in Rat Hepatocyte Cultures, Diabetologia, (1989), vol. 32, pp. 416-420.
Leyer et al, The role of the C-terminus of the insulin B-chain in modulating structural and functional properties of the hormone, International Journal of Peptide & Protein Research, vol. 46, No. 5, Nov. 1995, pp. 397-407.
Sanger, F., et. al., The Amide Groups of Insulin, The Biochemical Joumal, (1955) vol. 59, No. 3, pp. 509-518.
Schellenberger et al., Attempts for Quanitfying the S′ Subsite Specificity of Serine Proteases, Advances in the Biosciences, Peptides and Proteases: Recent Advances; Selected Papers Presented At the 2nd International Meeting on the Molecular and Cellular Regulation of Enzyme Activity, vol. 65, (1987), pp. 159-166.
Schellenberger et al., Protease-Catalyzed Kinetically Controlled Peptide Synthesis, Angewante Chemie, International Ediition, vol. 30, No. 11, 1991, pp. 1437-1449.
The Effect of Intensive Treatment of Diabetes on the Developement and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus, The New England Journal of Medicine vol. 329, No. 14, pp. 977-986 (1993).

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