Amelioration of Dupuytren's disease

Details Amelioration of Dupuytren's disease Amelioration of Dupuytren's disease

2007-12-18

2007-12-18

Naff, David M. (Department: 1651)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

C424S094100, C424S094630, C435S177000

Reissue Patent

active

11094753

ABSTRACT:
The cords of Dupuytren's disease are injected with collagenase, the hand is immediately immobilized and maintained immobile for several hours. The cord becomes relaxed or ruptured, relieving the hand contracture of the disease.

REFERENCES:
patent: 4338300 (1982-07-01), Gelbard
patent: 5589171 (1996-12-01), Wegman
patent: 543521 (1993-05-01), None
patent: 2 292 521 (1996-02-01), None
Journal of Hand Surgery 1996, vol. 21(3), pp. 490-495.
R. Berkow, “The Merck Manual of Diagnosis and Therapy,” published 1982 (14thEd.) Merck & Co., see p. 1602.
“Stedmans Medical Dictionary” published 1979 (23rdEd), The Williams & Wilkins Company, see p. 314.
Ippolito, et al., “Experimental Study on the Use of Collagenase in Localized Connective Tissue Fibrosis,”Ital. J. Orthop, Traumatol., 1/2: 279-290 (1975).

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