Ameliorant for chemical treatment of cancer

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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Reexamination Certificate

active

07462601

ABSTRACT:
An ameliorating agent for cancer chemotherapy is disclosed, which comprises a chromanol glycoside represented by the following general formula (1)(wherein R1, R2, R3, and R4, which are identical or different from each other, stand for a hydrogen atom or a lower alkyl group, R5stands for a hydrogen atom, a lower alkyl group, or a lower acyl group, X stands for a monosaccharide residue or an oligosaccharide residue optionally having the hydrogen atom of the hydroxyl group in the saccharide residue substituted with a lower alkyl group or a lower acyl group, n is an integer in the range of 0-6, and m is an integer in the range of 1-6).According to this invention, a novel ameliorating agent for cancer chemotherapy is provided which acts safely and effectively in a small dosage to enhance the carcinostatic action of an anti-cancer agent in cancer chemotherapy and repressing side effects by cancer chemotherapy as well.

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Igaku-No-Ayumi (Progress of Medical Science), 1993, vol. 164, No. 5, pp. 376-379.
European Search Report for Application No. EP 02 70 7164 dated Jan. 15, 2008.

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