Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2008-05-27
2008-05-27
Kemmerer, Elizabeth C. (Department: 1649)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S006120, C435S069100, C435S069700, C435S069800, C435S212000, C435S219000, C435S226000, C435S252300, C435S254110, C435S320100, C435S325000, C530S300000, C530S350000, C536S024100
Reexamination Certificate
active
10652045
ABSTRACT:
The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. The invention further provides a modified APP protein and associated nucleic acids, peptides, vectors, cells, and cell isolates, and assays that are particularly useful for identifying candidate therapeutics for treatment or prevention of Alzheimer's disease.
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Bienkowski Michael J.
Gurney Mark E.
Heinrikson Robert L.
Parodi Luis A.
Yan Riqiang
Emch Gregory S.
Kemmerer Elizabeth C.
Marshall & Gerstein & Borun LLP
Pharmacia & Upjohn Company
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