Alvac poxvirus-rabies compositions and combination compositions

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...

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4242041, 4242011, 4242021, 4242051, 4242181, 4242241, 4353201, 435 693, 4351723, 4352351, 4352523, 530350, 530826, 514 2, A61K 39275, A61K 39295, A61K 39205

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active

058434569

ABSTRACT:
Attenuated recombinant viruses containing DNA encoding a rabies virus antigen in a "cocktail" or combination or multivalent compositions well as methods for making and using the compositions, expression products therefrom, and antibodies generated, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The compositions and products therefrom and antibodies generated have several preventive, therapeutic and diagnostic uses.

REFERENCES:
patent: 5494807 (1996-02-01), Paoletti et al.
Benmansour A, 1985, Annales del'Instistu Pasteur-virologie, vol. 136 E, No. 2, pp. 167-173. (Abstract only).
Wiktor, T. et al, 1984, PNAS, vol. 81, pp. 7194-7198.
Taylor, J. et al, 1991, Vaccine, vol. 9, pp. 190-193.
Tartaglia, J. et al, 1992, Virology, vol. 188, pp. 217-232.
Cooper, P. et al., 1991, Obiettivie Documenti Veterinari, vol. 12 (10), pp. 25-30. (Abstract is enclosed).

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