Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1974-06-07
1976-09-07
Ore, Dale R.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
424 66, A61K 732
Patent
active
039795101
ABSTRACT:
Anti-perspirant complexes are provided which comprise a combination of a basic aluminum compound, a zirconium compound and a complex aluminum buffering compound containing in addition to aluminum two or more of the following: magnesium, calcium, sodium, carbonate, sulfate, hydroxyl and water. The various components are present in the complex in amounts such that the Al/Zr mole ratio is about 10:1 to 1:10 and the pH of an aqueous solution containing 5 to 15 weight percent of the complex (based on the oxides of aluminum and zirconium) is at least about 3. The basic aluminum compound may be any of the usual basic aluminum anti-perspirant salts, particularly the basic aluminum halides, and the zirconium compound may be a zirconium oxy salt and/or zirconium hydroxy salt. The complex aluminum buffer preferably contains among the additional groups or elements magnesium and/or carbonate. Examples of suitable complex aluminum buffers used include well-known antacid complexes such as hydrated magnesium aluminate, hydrated magnesium aluminum sulfate (HMAS), dihydroxy aluminum sodium carbonate (DASC), tetrahydroxy dialuminum magnesium carbonate (TDMC), and co-precipitates or co-dried mixtures of aluminum hydroxide with magnesium carbonate and/or calcium carbonate. The complexes may be used in conventional anti-perspirant forms, including aqueous solutions, aerosol sprays (including powder-in-oil aerosol sprays), as well as creams, lotions and cream sticks.
REFERENCES:
patent: 2923660 (1960-02-01), Hallman
patent: 2958626 (1960-11-01), Schenck et al.
patent: 3009860 (1961-11-01), Grote
patent: 3088874 (1963-05-01), Geary et al.
patent: 3725540 (1973-04-01), Wall
patent: 3773683 (1973-11-01), Aubert
Armour Pharmaceutical Company
Barber Frank T.
Ore Dale R.
Schwarze William W.
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