Aluminum ibuprofen pharmaceutical suspensions

Details Aluminum ibuprofen pharmaceutical suspensions Aluminum ibuprofen pharmaceutical suspensions

1981-05-11

1982-11-30

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Bacterium or component thereof or substance produced by said...

424317, 424361, 424362, A61K 4700, A61K 3128

Patent

active

043615805

ABSTRACT:
Aluminum ibuprofen pharmaceutical liquid suspensions having improved resistance to dissolution rate reduction upon storage containing aluminum ibuprofen, a suspending agent have a particle size below 50 microns, a water-soluble surface active agent, water, and preferably also from 5 to 30 grams of sucrose per 100 ml of suspension are disclosed, or its sweetening equivalent of glucose, fructose, sodium saccharin sodium cyclamate, or mixtures thereof.

REFERENCES:
patent: 3228831 (1966-01-01), Nicholson
patent: 3385886 (1968-01-01), Nicholson
patent: 3600437 (1971-08-01), Marshall
patent: 3636200 (1972-01-01), Zentner
patent: 3865857 (1975-02-01), Suzuki
patent: 3976674 (1976-08-01), Fields
patent: 3985779 (1976-10-01), Tanaka
patent: 4031243 (1977-06-01), Aparicio
patent: 4145440 (1979-03-01), Fitch
Berge, J. Pharm. Sci., vol. 66, Jan. 1977, pp. 1-19.
Nail, J. Pharm. Sci., vol. 65, Aug. 1976, pp. 1195-1198.
Remington's Pharm. Sci., 15th Ed., 1975, pp. 322-327, 1456-1460.
Chem. Abs., vol. 85, 1976, p. 522, Ab. No. 85:192387f.

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