Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1990-12-12
1991-08-13
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 49, A61K 718, A61K 716
Patent
active
050395149
ABSTRACT:
This invention relates to toothpaste containing an alumina hydrate abrasive and a source of fluoride.
According to the invention, there is provided a toothpaste containing a source of fluoride ions and unmilled, precipitated alumina trihydrate as an abrasive, wherein the alumina trihydrate particles have a median particle size of at least 3 micrometers.
The median particle size of the alumina trihydrate is preferably below 30 micrometers, more preferably from 5 to 20 micrometers, and most preferably 8 to 12 micrometers.
It has been found that the use of an unmilled alumina trihydrate, obtained by precipitation, substantially reduces the loss of available fluoride on storage whereas the use of a milled alumina trihydrate causes significant loss of available fluoride.
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Emery Anthony R.
Evans Kenneth A.
Wills Kevin J.
Alcan International Limited
Rose Shep K.
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