Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-11-23
2000-07-11
Schwartzman, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 693, 4352523, 43525411, 4353201, 435325, 435366, 536 235, 536 243, C12Q 168, C07H 2104, C12N 510, C12N 1563
Patent
active
060871105
ABSTRACT:
The present invention discloses that the normal melanogenic gene, gp75 gene, encodes a gene product, a 24 amino acid peptide of ORF3, which is processed to an antigenic cancer peptide recognized by T lymphocytes. The cancer peptide of the invention derived from ORF3 is recognized by cancer antigen specific T lymphocytes as a tumor rejection antigen. The products of this gene are promising candidates for immunotherapeutic strategies for the treatment and diagnosis of patients with cancer.
REFERENCES:
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Rosenberg Steven A.
Wang Rong-Fu
Schwartzman Robert A.
The United States of America as represented by the Department of
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