Altering memory by affecting staufen function

Details Altering memory by affecting staufen function Altering memory by affecting staufen function

2008-07-15

2011-11-29

Noble, Marcia S (Department: 1632)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Testing efficacy or toxicity of a compound or composition

C514S04400A, C514S04400A, C435S006120

Reexamination Certificate

active

08066972

ABSTRACT:
The present invention provides methods for screening a pharmaceutical agent for its ability to modulate long term memory formation, performance of a hippocampal-dependent cognitive task or STAUFEN function. The present invention also provides methods for modulating long term memory formation or performance of a hippocampal-dependent cognitive task by modulating staufen-dependent protein expression. The present invention further provides methods for treating a defect in long term memory formation associated with a defect in STAUFEN and methods for treating a defect in performance of a hippocampal-dependent cognitive task associated with a defect in STAUFEN.

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