Altered polypeptides with increased half-life

Details Altered polypeptides with increased half-life Altered polypeptides with increased half-life

2006-02-14

2006-02-14

Saunders, David (Department: 1644)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S069300, C435S069600, C435S243000, C435S320100, C435S325000, C435S410000, C536S023400, C536S023530

Reexamination Certificate

active

06998253

ABSTRACT:
Polypeptides that are cleared from the kidney and do not contain in their original form a Fc region of an IgG are altered so as to comprise a salvage receptor binding epitope of an Fc region of an IgG and thereby have increased circulatory half-life.

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