Alteration of rate and character of hair growth

Details Alteration of rate and character of hair growth Alteration of rate and character of hair growth

1990-10-24

1992-03-10

Friedman, S. J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

A61K 3170

Patent

active

050950070

ABSTRACT:
The rate and character of mammalian hair growth is altered by the topical application to the skin of a composition containing an inhibitor of the enzymes adenylosuccinate synthetase or aspartate transcarbamylase.

REFERENCES:
patent: 4720480 (1988-01-01), Shander
patent: 4885289 (1989-12-01), Breuer et al.
Chem. Abst. 95-143848e (1981).
DeYoung et al., Cancer Research, 38:3697-3701 (1978).
Gale et al., "Alanosine and hadacidin--Comparison of effects on adenylosuccinate synthetase", Biochem. Pharmacology, vol. 17, 2495-2498 (1968).
Tyagi et al., "Studies on the mechanism of resistance of selected murine tumors to L-Alanosine", Biochem. Pharmacology, vol. 30, 915-924 (1981).
Tyagi et al., "Prospects for the chemotherapy of cancer using analogs of L-aspartic acid", TIPS, vol. 4, 299-304 (1983).

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