Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-06-25
1992-03-17
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514470, 514563, 514880, A61K 3134, A61K 3142, A61K 31195
Patent
active
050969110
ABSTRACT:
The rate and character of mammalian hair growth is altered by the topical application to the skin of a composition containing an inhibitor of the enzyme gamma- glutamyl transpeptidase.
REFERENCES:
patent: 4720489 (1988-01-01), Shander
patent: 4885289 (1989-12-01), Breuer et al.
Ebling, F. J., D. Sc., PhD., "Hair", Journal of Investigative Dermatology, 67:98-106, (1976).
Cardo, P. et al., "Cellular and Chemical Changes of Dermis Accompanying Physiologic and Pathologic Hair-Changes", Hair Research, 244-250 (1981).
Lucky, Anne W., M.D., "Topical Antiandrogens", Arch Dermatol, 121:55-56 (1985).
Goldbarg, Julius A., M.D. et al., "A Method for the Colorimetric Determination of Gamma-Glutamyl Transpeptidase in Human Serum; Enzymatic Activity in Health and Disease", 44:2:127-133, (1963).
Minato, Sadamasa, "Isolation of Anthglutin, an Inhibitor of Gamma-Glutamyl Transpeptidase from Penicillum Oxalicum", Archives of Biochemistry and Biophysics, 192:1:235-240 (1979).
Gardell, Stephen J. et al., "Affinity Labeling of Gamma-Glutamyl Tarnspeptidase by Glutamine Antagonists", Febs Letts, 122:2:171-174 (1980).
Reed, Donald J. et al., "The Inhibition of Gamma-Glutamyl Transpeptidase and Gluthathione Metabolism of Isolated Rat Kidney Cells by L-(.sigma.S,5S)-.sigma.-Amino-3-Chloro-4, 5-Dihydro-5-Isoxazoleacetic Acid (At-125; NSC-163501)", Biochemical and Biophysical Research Communications, 94:4:1273-1277, (1980).
Kim, Young Pio et al., "Gamma-Glutamyl Transpeptidase Activity in Human Skin", Journal of Dermatology, 6:39-45, (1979).
Lucky, Anne W. et al., "Hair Follicle Response of the Golden Syrian Hamster Flank Organ to Continuous Testosterone Stimulation Using Silastic Capsules", J. Investig. Dermatology, 86:83-86 (1986).
Kaszynski, Edwin, "Stimulation of Hair Growth in the Flank Organs of Female Hamsters by Subcutaneous Testosterone Propionate and Its Inhibition by Topical Cyproterone Acetate: Dose-Response Studies", Brit. J. Dermatology, 109:565-569 (1983).
Richards et al., "Expression of Gamma-Glutamyl Transpeptidase Activity in the Developing Mouse Tooth, Intervertebral Disc, and Hair Follicle", Cancer Research, 42:4143-4151 (1982).
Chase et al., "Critical Stages of Hair Development and Pigmentation in the Mouse", Physiological Zoology, 24:1-8 (1951).
De Young et al., "Localization and Significance of Gamma-Glutamyltranspeptidase in Normal and Neoplastic Mouse Skin", Cancer Research, 38:3697-3701 (1978).
Kinoshita et al., "The Synthesis of Antiglutin and Its Analogues", Bull. Chem. Soc. Jpn., 54:2219-2220 (1981).
Minato, "Isolation of Antiglutin, an Inhibitor of y-Glytamyl Transpeptidase from Penicillum Oxalicum", Archives of Biochemistry and Biophysics, 192:235-240 (1979).
Ahluwalia Gurpreet S.
Harrington F. Eugene
Shander Douglas
LandOfFree
Alteration of rate and character of hair growth does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Alteration of rate and character of hair growth, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alteration of rate and character of hair growth will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1476094