Alteration of gallium biodistribution using indium complexes for

Details Alteration of gallium biodistribution using indium complexes for Alteration of gallium biodistribution using indium complexes for

1980-11-10

1984-05-15

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 128659, A61K 4300, A61K 4900

Patent

active

044487630

ABSTRACT:
Radiopharmaceutical compositions and methods for tumor tomography in mammals are disclosed, wherein radioactive gallium and non-radioactive indium are injected into said mammals whereby the affinity of said radioactive gallium for non-tumor tissues is decreased, resulting in enhanced imaging characteristics.

REFERENCES:
The Chemistry of Radiopharmaceuticals, ed. Heindel et al., Masson Pub. USA, Inc., New York (1978) pp. 155-168.
J. W. Triplett et al., "Alteration of Gallium Distribution in the Rat Using Periodically Related Elements", pp. 365-371 (1981).
Semin Nucl Med, 6: 331-334, 1976.
Semin Nucl Med, 8: 193-203, 205-218, 1978.
J Nucl Med, 21: 361-365, 421-425, 1980.
J Nucl Med, 17: 356-358, 1976.
J Nucl Med, 20: 248-251, 656, 1979.
Radiology, 131: 775-779, Jun. 1979.
Radiology, 130: 241-244, Jan. 1979.
Nuclear Pharmacy Papers, p. 68, date unknown at present.

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