Alteration of cell membrane with B7

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Cancer cell or component thereof

Reexamination Certificate

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Details

C435S354000, C435S355000, C435S366000, C435S372000, C435S375000, C514S012200, C530S350000, C530S816000, C536S023400

Reexamination Certificate

active

10312245

ABSTRACT:
Methods and compositions are provided for the persistent modification of cell membranes with exogenous proteins so as to alter the function of the cell to achieve effects similar to those of gene therapy, without the introduction of exogenous DNA. DNA sequences, the proteins and polypeptides embodying these sequences are disclosed for modulating the immune system. The modulations include down-regulation, up-regulation and apoptosis.

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