Alteration of ability of soluble CD4 fragments to bind HIV

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 91, 4351723, 4352351, 935 1, 935 9, 935 10, 935 11, 935 12, 935 65, C07H 1512, C12N 1500

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active

051091232

ABSTRACT:
DNA encoding modified soluble human CD4 fragments whose ability to bind to the HIV gp120 envelope protein is different from the ability of soluble human CD4 fragments; modified soluble human CD4 fragments having altered gp120 binding ability, methods of making such fragments and methods of using such fragments.

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