Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1980-07-15
1982-07-20
Love, Ethel G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
260465D, 260465F, 548170, C07D27774
Patent
active
043407404
ABSTRACT:
An alpha-thio-alpha-aryl-substituted alkanonitrile of the general formula ##STR1## wherein Ar represents an aromatic group, R represents a hydrogen atom or an alkyl group, R.sup.1 represents an alkyl group or an aromatic group, and Y represents an oxygen atom or a carbonyl group. The above compound can be prepared by reacting an alpha-aryl-substituted-alpha-thio-acetonitrile of the general formula ##STR2## wherein Ar, Y and R.sup.1 are as defined above, with an alkylating agent in the presence of a strong base. This compound is useful as an intermediate for producing an alpha-aryl-substituted alkane-carboxylic acid of the general formula ##STR3## wherein Ar, Y and R.sup.1 are as defined above.
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Mitamura Shuichi
Ogura Katsuyuki
Tsuchihashi Genichi
Love Ethel G.
Sagami Chemical Research Center
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