Alpha.sub.2 -antagonistic 2-(4,5-dihydro-1H-imidazol-2-yl)-pyrro

Details Alpha.sub.2 -antagonistic 2-(4,5-dihydro-1H-imidazol-2-yl)-pyrro Alpha.sub.2 -antagonistic 2-(4,5-dihydro-1H-imidazol-2-yl)-pyrro

1985-08-28

1986-10-14

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548348, A61K 31415, C07D48706

Patent

active

046173137

ABSTRACT:
Pyrrolo[3,2,1-hi]indole derivatives, in the form of racemates or optically active isomers, of formula (I) ##STR1## in which R is a hydrogen atom or C.sub.1 -C.sub.4 alkyl and R.sub.1 and R.sub.2, which may be the same or different, are hydrogen, halogen or C.sub.1 -C.sub.4 alkyl and their pharmaceutically acceptable acid addition salts are useful as .alpha..sub.2 -antagonists.

REFERENCES:
patent: 3671541 (1972-06-01), Bormann et al.
patent: 4391814 (1983-07-01), Vorbruggen
patent: 4411908 (1983-10-01), Chapleo et al.

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