.alpha..sub.2 -adrenergic receptor antagonists as modifiers of g

Details .alpha..sub.2 -adrenergic receptor antagonists as modifiers of g .alpha..sub.2 -adrenergic receptor antagonists as modifiers of g

1985-09-18

1987-06-16

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514212, 514222, 514226, 514228, 514231, 514234, 514235, 514253, 514256, 514280, 514275, A61K 3144, A61K 3155, A61K 31505

Patent

active

046736808

ABSTRACT:
Selective .alpha..sub.2 -adrenergic receptor antagonists are effective in modifying gastrointestinal motility in a manner useful in the treatment of colonic spasm, irritable bowel syndrome and constipation.

REFERENCES:
patent: 3132147 (1964-05-01), Schopf et al.
Opalko et al., Indoquinolizines Chem. Abst. 96:162676j.
Kluze et al., Chem. Abstr. 91:204200d.

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