[.alpha.,.omega.-bis(diphenylphosphino)hydrocarbon]bis[(thiosuga

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 171, 536122, A61K 3170, C07H 510

Patent

active

046457569

ABSTRACT:
This invention relates to [.alpha.,.omega.-bis(diphenylphosphino)hydrocarbon]bis[(thiosugar)gold] and bis[(selenosugar)gold] derivatives, pharmaceutical compositions comprising an effective tumor cell growth-inhibiting amount of such a derivative, and a method of treating tumor cells sensitive to such a derivative which comprises administering a tumor cell growth-inhibiting amount of such a derivative to an animal afflicted by said tumor cells.

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patent: 4201775 (1980-05-01), Filan et al.
Sutton et al., J. Med. Chem., 15(11), 1095-98 (1972).
Mirabelli et al., Proc. Amer. Assn. Cancer Res., 25, 367 (1984).
Simon et al., Cancer Res., 41, 94 (1981).
Mirabelli et al., Cancer Res., 45, 32 (1985).
Struck et al., J. Med. Chem. 9, 414-16 (1966).

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