.alpha.-Methylthio-.alpha.-(p-phthalimidophenyl)-propionic acid

Details .alpha.-Methylthio-.alpha.-(p-phthalimidophenyl)-propionic acid .alpha.-Methylthio-.alpha.-(p-phthalimidophenyl)-propionic acid

1980-06-04

1981-12-29

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D20948

Patent

active

043082084

ABSTRACT:
The present invention provides .alpha.-methylthio-.alpha.-(p-phthalimidophenyl)-propionic acid and its esters of the formula: ##STR1## wherein R' represents H or C.sub.1 -C.sub.4 alkyl. The subject compounds are useful as intermediates e.g. for Indoprofen.

REFERENCES:
patent: 3600437 (1971-08-01), Marshall et al.
Nannini et al., Arzneim.-Forsch., 23, Nr. 8 (1973), 1-oxo-2-substituted isoindoline derivatives.
Bonner, J.A.C.S. 74,1034 (1952).
Organic Synthesis Coll., vol. IV, pp. 58-62.
Nannini et al., Arzneim. Forsch. (Drug. Res.) 23(8), 1090 (1973).

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