Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Patent
1995-01-31
1998-12-22
Stanton, Brian R.
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
435 691, 435 711, 4351723, 935 34, 935 52, 935 70, C12N 1509, C12N 1511, C12N 1512, C12P 2100
Patent
active
058522247
ABSTRACT:
The present invention utilizes genetic engineering techniques to prepare non-human transgenic mammals that express human .alpha.-lactalbumin in their milk at a concentration of 2 mg/ml or greater. The invention also includes methods of preparing human .alpha.-lactalbumin in, for example, mice and cows. Also taught are methods for preparing human .alpha.-lactalbumin in which from one to four of its natural phenylalanine residues have been substituted by another amino acid.
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Cooper Julian David
Schnieke Angelika Elisabeth
PPL Therapeutics (Scotland) Limited
Stanton Brian R.
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