Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide
Patent
1984-04-24
1987-09-22
Martinell, James
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using tissue cell culture to make a protein or polypeptide
435 68, 435 71, 435 91, 4351723, 435243, 435253, 435811, 435317, 536 27, 935 11, 935 18, 935 29, 935 72, 935 73, C12P 2102, C12P 2100, C12P 2104, C12P 1934, C12N 1500, C12N 100, C12N 120, C07H 2104
Patent
active
046955437
ABSTRACT:
A cloned human alpha-interferon Gx-1 gene, plasmids containing the human alpha-interferon Gx-1 gene, and microorganisms transformed by those plasmids are disclosed. Also disclosed is the polypeptide, alpha-interferon Gx-1.
REFERENCES:
patent: 4456748 (1984-06-01), Goeddel et al.
Maeda et al, "Construction and Identification of Bacterial Plasmids Containing Nucleotide Sequence for Human Leukocyte Interferon", Proc. Natl. Acad. Sci. USA 77: 7010 (1980).
Science, vol. 212, 1159, Jun. 5, 1981 R. M. Lawn et al.
Nature, vol. 287, no. 4781, 408, Oct. 1980, Allen et al.
Goeddel, D. V., et al. Nature 287 (5781): 411-416 (1980); 209:20-26 (1981).
Brack, C. et al., Gene 15:379-394 (1981).
Nagata, S., et al. Nature 284:316-20 (1980).
Streuli, M., et al. Science 209:1343-47 (1980).
Goeddel, D. V., et al., Nucleic Acids Research 8:4057-4074.
Taniguichi, T., et al., Nature 285:547-49 (1980).
Taniguichi, T. et al., Proc. Natl. Acad. Sci. USA 77:5230-5233.
Bristol-Myers Company
Martinell James
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