Alpha-helix mimetics and methods relating to the treatment...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S262100, C540S524000, C544S256000, C544S282000

Reexamination Certificate

active

07915251

ABSTRACT:
The invention provides α-helix mimetic structures of formula (I) with the definitions of A, B, D, E, G, W, R1and R2as set out in the description and a chemical library relating thereto. The compounds, pharmaceutical compositions comprising the compounds, and methods of the invention using the compounds, relate to the treatment of diseases including fibrosis, such as pulmonary fibrosis.

REFERENCES:
patent: WO 97/15577 (1997-05-01), None
patent: WO 01/00210 (2001-01-01), None
patent: WO 01 16135 (2001-03-01), None
U.S. Appl. No. 11/594,575, filed Nov. 2006, Kahn M.
Dorwald FZ, “Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design,” Wiley-VCH Verlag GambH & Co. KGaA, 2005, Preface.

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