.alpha.-halogenated dicarboxylic acids, pharmaceutical compositi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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Details

514547, 514616, 560192, 562596, 564160, A61K 3119, A61K 31225, A61K 3116, C07C 5532

Patent

active

049083856

ABSTRACT:
The present invention provides pharmaceutical compositions containing at least one .alpha.-halogenated dicarboxylic acid of the general formula: ##STR1## wherein Hal is a chlorine, bromine or fluorine atom, R is a hydrogen atom or Hal and m is a number of from 4 to 16, and/or at least one pharmacologically acceptable salt, ester or amide thereof.
The present invention also provides new compounds of general formula (I) but in which m is a number of from 8 to 16 and processes for the preparation thereof.

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Treibs et al., Chem. Ber., 93, 2198-2208, (1960).
Chem. Abstr., 76, 55097m: Cherepenko, (1972).

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