.alpha.-glycosyl hesperidin and its uses

Details .alpha.-glycosyl hesperidin and its uses .alpha.-glycosyl hesperidin and its uses

1994-11-28

1997-05-06

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 8, 514 27, 426590, 426658, A61K 3170

Patent

active

056271573

ABSTRACT:
.alpha.-Glycosyl hesperidin, a novel hesperidin derivative wherein equimolar or more D-glucose residues are bound to hesperidin via the .alpha.-bond, is formed by a saccharide-transferring enzyme in a liquid containing hesperidin and .alpha.-glucosyl saccharide. The .alpha.-glycosyl hesperidin is easily recovered from the reaction mixture with a synthetic macroporous resin. .alpha.-Glycosyl hesperidin is superior in water-solubility, substantially tasteless and odorless, free of toxicity, and readily hydrolyzable in vivo into hesperidin and D-glucose to exhibit the physiological activity inherent to hesperidin. Thus, .alpha.-glycosyl hesperidin is favorably usable in vitamin P-enriching agents, foods, beverages, tobaccos, foods, pet foods, pharmaceuticals for susceptive diseases, cosmetics and plastics.

REFERENCES:
patent: 2700047 (1955-01-01), Wilson
patent: 4521410 (1985-06-01), Holick et al.
The Merck Index, ninth edition, Published by Merck & Co., Inc., (1976) pp. 110-111, No. 855.
Rathi et al., Acta Vitaminol. Enzymol. 1983 5(5), 255-261.

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