.alpha.-glucosidase inhibitors

Details .alpha.-glucosidase inhibitors .alpha.-glucosidase inhibitors

1990-09-17

1992-03-17

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

514 25, 514866, 514909, A61K 3170, C07H 1526, C07H 19044

Patent

active

050970232

ABSTRACT:
This invention relates to novel N-glycosyl derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol, to the chemical processes for their preparation, to their .alpha.-glucosidase inhibiting properties, and to their end-use application in the treatment of diabetes, obesity and those diseases associated with retroviruses, particularly the HIV virus reported to be the causative of the acquired immune deficiency syndrome (AIDS).

REFERENCES:
patent: 4639436 (1987-01-01), Junge et al.
Grant & Hackh's Chemical Dictionary, Fifth Edition, McGraw-Hill Book Company, N.Y., N.Y. 1987, p. 313.
Fleet et al., Tetrahedron, 42, 20, 5685 (1986).
Fleet et al., (FEBS) Elsevier Science Publishers B.V., 237 1,2, 128-132 (1988).

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