.alpha.-fluoro-.alpha.-tetrazolyl-phenylmethyl derivatives usefu

Details .alpha.-fluoro-.alpha.-tetrazolyl-phenylmethyl derivatives usefu .alpha.-fluoro-.alpha.-tetrazolyl-phenylmethyl derivatives usefu

1991-12-09

1993-07-13

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548250, 548251, 548252, 548253, 548254, A61K 3141, C07D25704

Patent

active

052273938

ABSTRACT:
Compounds of formula I ##STR1## wherein Z, R, R.sub.1, R.sub.2 and X are as defined in the description, have valuable pharmaceutical properties and are effective especially against tumours. They are prepared in a manner known per se.

REFERENCES:
patent: 4657921 (1987-04-01), Frick et al.
patent: 4657921 (1987-04-01), Frick et al.
patent: 4916144 (1990-04-01), Strehlke et al.
patent: 4916144 (1990-04-01), Strehlke et al.
patent: 5006543 (1991-04-01), Boyle
patent: 5006543 (1991-04-01), Boyle
patent: 5021434 (1991-06-01), Strehlke et al.
patent: 5021434 (1991-06-01), Strehlke et al.
patent: 5045558 (1991-09-01), Strehlke et al.
patent: 5045558 (1991-09-01), Strehlke et al.
Bhatnagar et al., J. Steroid Biochem. Molec. Biol. vol. 37, No. 6, pp. 1021-1027, 1990.
Jones et al., Estrogen Synthetase Inhibitors, J. Med. Chem. 1990, 33, 416-429.
Taylor, et al., Aromatase Inhibition by 5-Substituted Pyrimidines and Dihydropyrimidines, J. Med. Chem. 1987, 30, 1359-1365.
Biagi et al., Il Farmaco-Ed. Sc.-vol. 43, 597-611 (1988).

Affiliated with

Also associated with

Rating

.alpha.-fluoro-.alpha.-tetrazolyl-phenylmethyl derivatives usefu does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with .alpha.-fluoro-.alpha.-tetrazolyl-phenylmethyl derivatives usefu, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .alpha.-fluoro-.alpha.-tetrazolyl-phenylmethyl derivatives usefu will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2312252