.alpha.-fluoro-.alpha.-(1,2,3-triazolyl)-phenylmethyl derivative

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...


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548255, A61K 3141, C07D24904




Compounds of formula I ##STR1## wherein Z, R, R.sub.1, R.sub.2 and X are as defined in the description, have valuable pharmaceutical properties and are effective especially against tumors. They are prepared in a manner known per se.

patent: 4609666 (1986-09-01), Hirsch et al.
patent: 4845227 (1989-07-01), Hirsch et al.
Jones et al, "Estrogen Synthetase Inhibitors, etc." J. Med. Chem (1990), 33, 416-429.


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