Alpha-fetoprotein peptides and uses thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues

Reexamination Certificate

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C530S329000, C530S330000, C514S016700, C514S017400, C514S018700

Reexamination Certificate

active

07598342

ABSTRACT:
The invention relates to compounds that include peptide and peptidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.

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Parikh et al., “Prevention ofN-Methyl-N-Nitrosourea-Induced Breast Cancer by α-Fetoprotein (AFP)—Derived Peptide, a Peptide Derived from the Active Site of AFP”,Clin Cancer Res, 2005; 11(23) Dec. 1, 2005; 8512-8520.
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