Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1997-02-19
1999-08-24
Gupta, Yogendra N.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514416, 514535, 514561, 514568, 514647, 514649, 546334, 546336, 548494, 548504, 560 34, 560 35, 560 55, 562426, 562429, 562430, 562433, 564149, 564162, 564164, 564336, A61K 31215, A61K 31195, A61K 3123, C07C22914, C07C21100, C07C21302
Patent
active
059425440
ABSTRACT:
The present application describes m-amidino phenyl analogs of formula I: ##STR1## wherein D can be amidino and E can be phenyl, which are useful as inhibitors of factor Xa.
REFERENCES:
patent: 5187157 (1993-02-01), Kettner et al.
patent: 5492895 (1996-02-01), Vlasuk et al.
Tidwell et al., Thrombosis Research 1980, 19, 339-349, "Strategies for Anticoagulation with Synthetic Protease Inhibitors. Xa Inhibitors Versus Thrombin Inhibitors".
Cacciola Joseph
Fevig John Matthew
Maduskuie, Jr. Thomas Peter
Quan Mimi Lifen
Stouten Petrus Fredericus Wilhelmus
DuPont Pharmaceuticals Company
Gupta Yogendra N.
Vance David H.
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